With over 40 years of experience in automated liquid handling, the Tomtec Quadra5 Liquid Handling Workstation sets the standard for a cost-effective liquid handling workstation for life science applications. The workstation is engineered around a reliable fixed-head air displacement syringe design that services a six-station shuttle. The six stations can support a wide range of accessories for automating sample preparation, like solid phase extraction (SPE), magnetic bead cleanup, as well as dilutions and standards additions. With an optional plate-stacker, the Quadra5 can be used to queue up to 50 assays. With an easy to learn, user-friendly WIN 10 64-bit graphical interface, the Quadra4 delivers speed, flexibility, and precision.
Each Quadra5 Liquid Handling Workstation is manufactured in our Connecticut and New Jersey facilities. Tomtec engineers work with your research team to understand your analytical sample requirements and then recommend the best possible solutions at the best possible price. When the Quadra4 Liquid Handling Workstation is delivered to your laboratory, Tomtec engineers install and test your system and familiarise your team on how to get the most value from your Tomtec investment. With both air displacement pipetting, in conjunction with an optional indexing microplate stage, the Quadra4 Liquid Handling Workstation enables the support of complex pipette workloads found on workstations that cost five times its price. In addition, the optional automated plate stackers provide true walk-away assay automation.
The Quadra5 provides:
- Highly precise and consistent, accurate pipetting for 24, 96, 384 ANSI microplates.
- Wide spectrum flow rate with the sensitivity and utility to handle a wide range of aqueous and organic solutions within the same workflow.
- Process logs for assay validation and QC with full barcode support and LIMS integration.
- Intuitive and flexible Graphical User Interface (GUI) for set-up and monitoring workflows
Specifications
| Bioanalytical Applications | General Capabilities | Precise Assay Automation |
| 450ul tips with a cannula to access deep well plates | Flexibility to support 96 well pipetting with either 450ul, 250ul, 50ul, or 20ul clear plastic tips | Precision 96-well positive displacement pipetting at 60ul to 0.5ul @ ± 2.5% |
| Aqueous, to organic, to aqueous, without a tip change | Automated serial dilution with either 8 or 12 tips | Precision 384 well positive displacement pipetting at 60ul to 0.5ul@ ± 2.5% |
| Manual or automated vacuum box options | Pipette multiple reagents, within the same tip, using air gap separation to accelerate workflows | Automated 96 to 384 to 1536 reformatting |
| Stacker in-feed/out-feed for microplates and reservoirs provides walk-away automation | Non-contact dispensing | |
| Six-station shuttle to support multiple microplates and reservoirs | Pipetting heads configured for 24 to 96 to 384 and/or 1536 well assays, as well as specialised heads. | |
| SPE Liquid/Liquid extraction, optional positive pressure SPE | Cost-effective non-sterilised and sterilised pipettes available directly from Tomtec | |
| Ultrasonic tip washing and magnetic bead toolsets are available |
Applications
Sample preparation for qualitative and quantitative LC-MS/MS
Sample preparation and transfer from 24-vial formats to microtiter plate formats
24 and 96 tip pipetting heads are ideal for blood/fecal samples in vials for prep for GC-MS, then transfer to 96-well plates for LC-MSMS
High Throughput Screening for NME
Solid Phase Extraction
Genomics – Sample Preparation and PCR
Drug Testing (metabolites -NIDA-5)