Key Features
- Frozen aliquotting without thawing – helps eliminate damaging freeze-thaw cycles.
- Ultra-low temperature processing – chilled working area maintains samples between approximately −80°C and −150°C using LN₂.
- Multiple aliquots from one sample – extract up to five frozen aliquots from a single 2.0 mL vial.
- 10 µL to 250 µL aliquot range – suitable for a variety of downstream applications.
- Approximately 60 seconds per aliquot for efficient sample processing.
- Laser targeting system enables accurate coring of selected areas within frozen tissue samples.
- Single-use, nuclease-free coring probes help minimise sample-to-sample carryover and contamination.
- Flexible sample compatibility accommodates a range of vial types, sample containers and volumes.
- Compact benchtop footprint for integration into laboratory workflows.
- User-friendly touchscreen interface with easily accessible user-specific protocols.
- Removable guard assists with straightforward cleaning and routine maintenance.
Compatible Sample Types
The CXT 353 can be used with a broad range of frozen biological samples, including:
- Tissue
- Faecal samples
- Serum
- Plasma
- Whole blood
- Urine
- Other biological fluids
Benefits of Frozen Aliquotting
Frozen aliquotting allows laboratories to access smaller portions of valuable samples while keeping the remaining parent material frozen.
This can help:
- Preserve temperature-sensitive and labile molecules.
- Reduce analyte degradation associated with repeated freeze-thaw cycles.
- Improve reproducibility between studies.
- Preserve remaining parent samples for future or retrospective analysis.
- Maximise utilisation of rare, limited or difficult-to-replace specimens.
- Generate smaller aliquots that can thaw more rapidly when required.
- Reduce manual cutting and handling of frozen tissue.
- Minimise direct handling of faecal samples.
- Access specific areas of frozen tissue for targeted analysis.
Applications
Ideal for laboratory workflows including:
Biobanking | Microbiome Research | Molecular Pathology | Bioanalysis | Biomarker Research | Clinical Research | Translational Research | Sample Preparation
Why Choose the CXT 353?
For laboratories managing valuable frozen specimens, maintaining sample integrity is critical. The CXT 353 enables researchers to access the amount of material required for an experiment while preserving the remainder of the parent sample at ultra-low temperature.
By combining precise frozen coring with LNâ‚‚ cooling, single-use probes and targeted tissue sampling, the system helps laboratories protect sample quality, maximise sample utilisation and improve consistency across downstream analyses.
